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Anastrozole is called non-steroidal aromatase inhibitors. Anastrozole tablets USP 1mg is used to treat breast cancer in women whose breast cancer has worsened after taking tamoxifen & who have experienced menopause . Anastrozole has been used for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism, so it has been used to reduce and prevent symptoms of excess estrogens; gynecomastia and water retention.